Is it the best for barista robots to serve like humans? A multidimensional anthropomorphism perspective

The COVID-19 pandemic has accelerated the use of contactless service robots in hospitality industries. However, the key drivers of consumer behaviors against service robots have been ill-understood. This study examines the interactive relationships between the physical (visual features) and psychological (service autonomy) dimensions of service-robot anthropomorphism and their impacts on consumer acceptance of service robots. Adopting an experimental vignette method (EVM) with 402 participants, the study reveals that the impacts of visual features on consumers' intention are affected by the level of service robots' autonomy;particularly, consumers showed the highest intention when the robots have medium visual features and high autonomy while their intention became lower for the same level of visual features with low autonomy. Interestingly, consumers showed the lowest intention with high level visual features, regardless of the levels of autonomy. Our results also show that human identity threats and consumer resistance play a significant counterproductive mechanism between service robot anthropomorphism and consumers' intention. © 2022 Elsevier Ltd

Screening coronavirus and human proteins for sialic acid binding sites using a docking approach

The initial step of interaction of some pathogens with the host is driven by the interaction of glycoproteins of either side via endcaps of their glycans. These end caps consist of sialic acids or sugar molecules. Coronaviruses (CoVs), including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are found to use this route of interaction. The strength and spatial interactions on the single molecule level of sialic acids with either the spike (S) protein of SARS coronaviruses, or human angiotensin-converting enzyme 2 (ACE2) and furin are probed and compared to the binding modes of those sugar molecules which are present in glycans of glycoproteins. The protocol of using single molecules is seen as a simplified but effective mimic of the complex mode of interaction of the glycans. Averaged estimated binding energies from a docking approach result in preferential binding of the sialic acids to a specific binding site of the S protein of human coronavirus OC43 (HCoV-OC43). Furin is proposed to provide better binding sites for sialic acids than ACE2, albeit outweighed by sites for other sugar molecules. Absolute minimal estimated binding energies indicate weak binding affinities and are indifferent to the type of sugar molecules and the proteins. Neither the proposed best binding sites of the sialic acids nor those of the sugar molecules overlap with any of the cleavage sites at the S protein and the active sites of the human proteins. © 2021, AIMS Biophysics. All rights reserved.